The apo‐form of the Vibrio cholerae replicative helicase DnaB is a labile and inactive planar trimer of dimers
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14403
Abstract: To enable chromosomal replication, DNA is unwound by the ATPase molecular motor replicative helicase. The bacterial helicase DnaB is a ring‐shaped homo‐hexamer whose conformational dynamics are being studied through its different 3D structural states adopted… read more here.
Keywords: trimer dimers; dnab; vibrio cholerae; replicative helicase ... See more keywords
The replicative helicase CMG is required for the divergence of cell fates during asymmetric cell division in vivo
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DOI: 10.1038/s41467-024-53715-2
Abstract: The mechanisms that enable differential gene expression in daughter cells produced by asymmetric cell divisions are not well understood. We discovered that the eukaryotic replicative helicase CMG (Cdc45-MCM-GINS) is required for this process in C.… read more here.
Keywords: replicative helicase; cell; cell division; cmg ... See more keywords
Frequent nonhomologous replacement of replicative helicase loaders by viruses in Vibrionaceae
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DOI: 10.1073/pnas.2317954121
Abstract: Significance In recent years, numerous prokaryotic genomes have been sequenced. However, these genomes contain many genes with unknown functions, which is a fundamental obstacle to the effective use of genomic information. To solve a part… read more here.
Keywords: replacement replicative; genetics; replicative helicase; nonhomologous replacement ... See more keywords