Pterocarpus marsupium extract extends replicative lifespan in budding yeast.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00418-x
Abstract: As the molecular mechanisms of biological aging become better understood, there is growing interest in identifying interventions that target those mechanisms to promote extended health and longevity. The budding yeast Saccharomyces cerevisiae has served as… read more here.
Keywords: budding yeast; marsupium extract; replicative lifespan; lifespan ... See more keywords
A High-Throughput Screen for Yeast Replicative Lifespan Identifies Lifespan-Extending Compounds.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.11.002
Abstract: Progress in aging research is constrained by the time requirement of measuring lifespans. Even the most rapid model for eukaryotic aging, the replicative lifespan of Saccharomyces cerevisiae, is technically limited to only several lifespan measurements each… read more here.
Keywords: technique; extending compounds; replicative lifespan; lifespan ... See more keywords
PMT1 deficiency extends the shortened replicative lifespan of TED1-deficient yeast in a Hac1p-dependent manner
Sign Up to like & getrecommendations! Published in 2018 at "FEMS Microbiology Letters"
DOI: 10.1093/femsle/fny234
Abstract: Protein O-mannosyltransferase-1 (Pmt1p) deficiency extends the replicative lifespan (RLS) of Saccharomyces cerevisiae, which is related to the activation of the unfolded protein response (UPR), an important pathway for alleviating endoplasmic reticulum (ER) stress. Trafficking of… read more here.
Keywords: ted1; replicative lifespan; deficiency extends; pmt1 deficiency ... See more keywords
Proline metabolism regulates replicative lifespan in the yeast Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Cell"
DOI: 10.15698/mic2019.10.694
Abstract: In many plants and microorganisms, intracellular proline has a protective role against various stresses, including heat-shock, oxidation and osmolarity. Environmental stresses induce cellular senescence in a variety of eukaryotes. Here we showed that intracellular proline… read more here.
Keywords: lifespan yeast; intracellular proline; proline; replicative lifespan ... See more keywords