Alphavirus vector-based replicon particles expressing multivalent cross-protective Lassa virus glycoproteins
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.12.046
Abstract: Lassa virus (LASV) is the most prevalent rodent-borne arenavirus circulated in West Africa. With population at risk from Senegal to Nigeria, LASV causes Lassa fever and is responsible for thousands of deaths annually. High genetic… read more here.
Keywords: replicon particles; cross; alphavirus vector; lassa virus ... See more keywords
West Nile virus infectious replicon particles generated using a packaging-restricted cell line is a safe reporter system
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03670-4
Abstract: West Nile virus (WNV) is a neurotropic pathogen which causes zoonotic disease in humans. Recently, there have been an increasing number of infected cases and there are no clinically approved vaccines or effective drugs to… read more here.
Keywords: replicon particles; replicon; cell line; virus ... See more keywords
High-Throughput Platform for Detection of Neutralizing Antibodies Using Flavivirus Reporter Replicon Particles
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14020346
Abstract: Flavivirus outbreaks require fast and reliable diagnostics that can be easily adapted to newly emerging and re-emerging flaviviruses. Due to the serological cross-reactivity among flavivirus antibodies, neutralization tests (NT) are considered the gold standard for… read more here.
Keywords: replicon; reporter; replicon particles; high throughput ... See more keywords