Pif1 is essential for efficient replisome progression through lagging strand G-quadruplex DNA secondary structures
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DOI: 10.1093/nar/gky1065
Abstract: Abstract Pif1 DNA helicase is a potent unwinder of G-quadruplex (G4) structures in vitro and functions to maintain genome stability at G4 sequences in Saccharomyces cerevisiae. Here, we developed and utilized a live-cell imaging approach… read more here.
Keywords: pif1 essential; lagging strand; replisome progression; progression ... See more keywords