Articles with "repolarisation" as a keyword



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Hysteretic Dynamics of Multi-Stable Early Afterdepolarisations with Repolarisation Reserve Attenuation: A Potential Dynamical Mechanism for Cardiac Arrhythmias

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-11355-1

Abstract: Some cardiovascular and non-cardiovascular drugs frequently cause excessive prolongation of the cardiac action potential (AP) and lead to the development of early afterdepolarisations (EADs), which trigger lethal ventricular arrhythmias. Combining computer simulations in APs with… read more here.

Keywords: repolarisation reserve; reserve attenuation; multi stable; repolarisation ... See more keywords
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Emerging therapeutic targets in the short QT syndrome

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Published in 2018 at "Expert Opinion on Therapeutic Targets"

DOI: 10.1080/14728222.2018.1470621

Abstract: ABSTRACT Introduction: Short QT Syndrome (SQTS) is a rare but dangerous condition characterised by abbreviated repolarisation, atrial and ventricular arrhythmias and risk of sudden death. Implantable cardioverter defibrillators (ICDs) are a first line protection against… read more here.

Keywords: short syndrome; therapeutic targets; repolarisation; channel ... See more keywords

Genetically-Determined Serum Calcium Levels and Markers of Ventricular Repolarisation: A Mendelian Randomization Study in the UK Biobank.

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Published in 2021 at "Circulation. Genomic and precision medicine"

DOI: 10.1161/circgen.120.003231

Abstract: Background - Electrocardiographic (ECG) markers of ventricular depolarisation and repolarisation are associated with an increased risk of arrhythmia and sudden cardiac death. Our prior work indicated lower serum calcium concentrations are associated with longer QT… read more here.

Keywords: mendelian randomization; repolarisation; serum calcium; markers ventricular ... See more keywords
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Assessment of myocardial repolarisation parameters in patients with familial Mediterranean fever

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Published in 2017 at "Cardiovascular Journal of Africa"

DOI: 10.5830/cvja-2016-074

Abstract: Summary Background: Familial Mediterranean fever (FMF) is a chronic, recurrent auto-inflammatory disease characterised by self-terminating attacks of fever and sterile polyserositis. The main cause of death in auto-inflammatory diseasesis cardiovascular events. Additionally, auto-inflammatory diseases have… read more here.

Keywords: familial mediterranean; myocardial repolarisation; repolarisation; repolarisation parameters ... See more keywords
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A rare cause of early repolarisation in an adolescent boy with chest pain: myocardial bridging

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Published in 2017 at "Cardiovascular Journal of Africa"

DOI: 10.5830/cvja-2016-088

Abstract: Summary Early repolarisation is a common electrocardiographic (ECG) finding characterised by J-point and ST segment elevation ≥ 0.1 mV in two or more adjacent leads. The ECG pattern of early repolarisation is relatively common in… read more here.

Keywords: chest pain; early repolarisation; repolarisation; adolescent boy ... See more keywords