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Published in 2019 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.1696
Abstract: Ubrogepant is a novel, oral calcitonin gene–related peptide receptor antagonist currently under US Food and Drug Administration (FDA) review for the acute treatment of migraine attacks. This double‐blind, four‐period crossover study compared the cardiac repolarization…
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Keywords:
single therapeutic;
cardiac repolarization;
healthy adults;
therapeutic supratherapeutic ... See more keywords
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Published in 2019 at "Heart and Vessels"
DOI: 10.1007/s00380-019-01383-4
Abstract: AbstractMyocardial ischemia changes the electrophysiological properties of the myocardium, but it is difficult to detect the abnormalities of depolarization and repolarization noninvasively in patients with coronary artery disease. Depolarization and repolarization abnormalities were retrospectively investigated…
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Keywords:
abnormal depolarization;
depolarization repolarization;
group;
coronary artery ... See more keywords
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Published in 2021 at "Fish Physiology and Biochemistry"
DOI: 10.1007/s10695-021-00983-0
Abstract: The spatial–temporal organization of the activation, repolarization and hemodynamics of the heart ventricle in rainbow trout, Oncorhynchus mykiss , adapted to a temperature of 5–7 °C, were studied from the normal sinus rhythm (21.6 ± 4.9 bpm) to the…
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Keywords:
heart;
repolarization;
heart ventricle;
hemodynamics ... See more keywords
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Published in 2020 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2019.12.022
Abstract: BACKGROUND Dispersion in ventricular repolarization is relevant for arrhythmogenesis. OBJECTIVE To determine the spatiotemporal effects of sympathetic stimulation on ventricular repolarization. METHODS In five anesthetized female open chested pigs ventricular repolarization was measured from the…
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Keywords:
stimulation;
repolarization;
lsgs;
ventricular repolarization ... See more keywords
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Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2016.11.251
Abstract: BACKGROUND The calcium sensitizer levosimendan is established for therapy of acutely decompensated congestive heart failure. Clinical experience suggests a possible proarrhythmic potential. The aim of the present study was to assess possible proarrhythmic effects and…
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Keywords:
levosimendan;
proarrhythmic potential;
experimental evidence;
repolarization ... See more keywords
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Published in 2018 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2017.12.003
Abstract: BACKGROUND Aim of the study was to find out which myocardial repolarization parameters predict reperfusion ventricular tachycardia and fibrillation (VT/VF) and determine how these parameters express in ECG. METHODS Coronary occlusion and reperfusion (30/30min) was…
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Keywords:
repolarization perfused;
predicts reperfusion;
repolarization;
perfused myocardium ... See more keywords
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Published in 2019 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2019.08.007
Abstract: BACKGROUND With increasing clinical use of Electrocardiographic Imaging (ECGI), it is imperative to understand the limits of this technique. The objective of this study is to evaluate a potential-based ECGI approach for activation and repolarization…
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Keywords:
pitfalls noninvasive;
activation repolarization;
repolarization;
activation ... See more keywords
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Published in 2020 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2020.02.003
Abstract: BACKGROUND Measuring repolarization characteristics is challenging and has been reserved for experienced physicians. In electrocardiographic imaging (ECGI), activation-recovery interval (ARI) is used as a measure of local cardiac repolarization duration. We hypothesized that repolarization characteristics,…
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Keywords:
arrhythmogenic substrate;
repolarization parameters;
use;
repolarization ... See more keywords
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Published in 2020 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2020.05.002
Abstract: Benign Early Repolarization is seen most commonly in young males and is thought to arise from left ventricular hypertrophy, vagal tone and hereditary predilection. This case describes an elderly man with Early Repolarization mimicking acute…
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Keywords:
segment elevation;
carotid stent;
repolarization;
early repolarization ... See more keywords
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Published in 2022 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2022.04.001
Abstract: PURPOSE Cardiac resynchronization therapy (CRT) reduces ventricular activation times and electrical dyssynchrony, however the effect on repolarization is unclear. In this study, we sought to investigate the effect of CRT and left ventricular (LV) remodeling…
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Keywords:
dispersion;
cardiac resynchronization;
cari dispersion;
resynchronization therapy ... See more keywords
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Published in 2021 at "Medical image analysis"
DOI: 10.1016/j.media.2021.102075
Abstract: Reliable patient-specific ventricular repolarization times (RTs) can identify regions of functional block or afterdepolarizations, indicating arrhythmogenic cardiac tissue and the risk of sudden cardiac death. Unipolar electrograms (UEs) record electric potentials, and the Wyatt method…
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Keywords:
unipolar electrograms;
method;
estimation;
wyatt method ... See more keywords