Mutation in KCNE1 associated to early repolarization syndrome by modulation of slowly activating delayed rectifier K+ current
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.01.030
Abstract: Background Recent studies have revealed that mutation in KCNE1, &bgr;‐subunits of cardiac potassium channel, involved in ventricular fibrillation. Whereas its role in early repolarization syndrome (ERS) is less well understood. Objective To study whether mutant… read more here.
Keywords: kcne1 associated; mutation kcne1; early repolarization; kcne1 ... See more keywords
Abstract 4139769: Fluoxetine, a Novel Therapeutic Strategy for Early Repolarization Syndrome Caused by a KCND3 Gain-of-Function Variant
Sign Up to like & getrecommendations! Published in 2024 at "Circulation"
DOI: 10.1161/circ.150.suppl_1.4139769
Abstract: Introduction: Kv4.3 encoded by KCND3 is an α-subunit of the I to channel and is highly expressed in both brain and heart. Several KCND3 variants have been shown to be related to inherited arrhythmias and… read more here.
Keywords: fluoxetine; effect; gain function; repolarization syndrome ... See more keywords
Atrial Fibrillation-triggered Ventricular Fibrillation in a Patient with Early Repolarization Syndrome.
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DOI: 10.2169/internalmedicine.8716-21
Abstract: A 54-year-old man with early repolarization syndrome (ERS) implanted with an implantable cardioverter-defibrillator (ICD) developed persistent atrial fibrillation (AF) three years after the implantation. Similarly, the remote monitoring system begun frequently detecting ventricular fibrillation (VF)… read more here.
Keywords: atrial fibrillation; fibrillation; ventricular fibrillation; early repolarization ... See more keywords