MPRAnator: a web-based tool for the design of massively parallel reporter assay experiments
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btw584
Abstract: Abstract Motivation With the rapid advances in DNA synthesis and sequencing technologies and the continuing decline in the associated costs, high-throughput experiments can be performed to investigate the regulatory role of thousands of oligonucleotide sequences… read more here.
Keywords: mpranator; tool; assay experiments; reporter assay ... See more keywords
Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target.
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DOI: 10.1136/gutjnl-2020-323665
Abstract: OBJECTIVES Chronic hepatitis B virus (HBV) infection is a leading cause of liver disease and hepatocellular carcinoma. A key feature of HBV replication is the synthesis of the covalently close circular (ccc)DNA, not targeted by… read more here.
Keywords: cell based; cccdna host; reporter assay; hbv cccdna ... See more keywords