Infrared Photoactivation Boosts Reporter Ion Yield in Isobaric Tagging.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c05398
Abstract: Isobaric tagging facilitates multiplexed experiments that can determine sequences and relative amounts of peptides in biological samples using tandem mass spectrometry (MSn). Limited reporter ion generation limits quantitative accuracy and precision. As reporter ions are… read more here.
Keywords: reporter ions; isobaric tagging; ion yield; ion ... See more keywords
Accurate, Sensitive, and Precise Multiplexed Proteomics Using the Complement Reporter Ion Cluster.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b04713
Abstract: Quantitative analysis of proteomes across multiple time points, organelles, and perturbations is essential for understanding both fundamental biology and disease states. The development of isobaric tags (e.g., TMT) has enabled the simultaneous measurement of peptide… read more here.
Keywords: tmt; sensitive precise; reporter ion; tmt ms3 ... See more keywords
Rapid Screening of Ellagitannins in Natural Sources via Targeted Reporter Ion Triggered Tandem Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27708-3
Abstract: Complex biomolecules present in their natural sources have been difficult to analyze using traditional analytical approaches. Ultrahigh-performance liquid chromatography (UHPLC-MS/MS) methods have the potential to enhance the discovery of a less well characterized and challenging… read more here.
Keywords: reporter; reporter ion; screening ellagitannins; natural sources ... See more keywords