A novel triplex isobaric termini labeling quantitative approach for simultaneously supplying three quantitative sources.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2017.11.004
Abstract: Benefiting from high sensitivity and great ability to measure multiple samples simultaneously, isobaric tandem Mass spectrometry (MS2) quantification has been widely applied for protein biomarker screening. Here, a newly developed isobaric MS2 quantification method named… read more here.
Keywords: isobaric termini; triplex qitl; termini; termini labeling ... See more keywords
Infrared Photoactivation Boosts Reporter Ion Yield in Isobaric Tagging.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c05398
Abstract: Isobaric tagging facilitates multiplexed experiments that can determine sequences and relative amounts of peptides in biological samples using tandem mass spectrometry (MSn). Limited reporter ion generation limits quantitative accuracy and precision. As reporter ions are… read more here.
Keywords: reporter ions; isobaric tagging; ion yield; ion ... See more keywords