Generation and characterization of West Nile pseudo‐infectious reporter virus for antiviral screening
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.02.006
Abstract: ABSTRACT West Nile virus (WNV), a mosquito‐borne flavivirus, is an important neurotropic human pathogen. As a biosafety level‐3 (BSL‐3) agent, WNV is strictly to BSL‐3 laboratories for experimentations, thus greatly hindering the development of vaccine… read more here.
Keywords: dgr ns1; reporter virus; wnv; gluc ... See more keywords
A Dengue type 2 reporter virus assay amenable to high-throughput screening.
Sign Up to like & getrecommendations! Published in 2020 at "Antiviral research"
DOI: 10.1016/j.antiviral.2020.104929
Abstract: Dengue virus (DV) is an important mosquito-borne flavivirus threatening almost half of the world's population. Prophylaxis and potent anti-DV drugs are urgently needed. Here, we developed a high content imaging-based (HCI) assay with DV type… read more here.
Keywords: amenable high; assay amenable; reporter virus; virus assay ... See more keywords
Generation and characterization of luciferase-secreting, single-round infectious DENV-2 reporter for functional antibody assays.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2021.114119
Abstract: Flavivirus reporters provide a robust tool for viral pathogenesis studies, anti- viral drug screening, disease diagnosis and functional antibody assays. In this study, we generated a luciferase-secreting, single-round reporter virus by replacing the capsid coding… read more here.
Keywords: reporter; reporter virus; luciferase; functional antibody ... See more keywords
Generation of a pdmH1N1 2018 Influenza A Reporter Virus Carrying a mCherry Fluorescent Protein in the PA Segment
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.827790
Abstract: Influenza A virus (IAV) is a major human pathogen associated with significant morbidity and mortality worldwide. Through serial passage in mice, we generated a recombinant pdmH1N1 2009 IAV, A/Guangdong/GLW/2018 (GLW/18-MA), which encodes an mCherry gene… read more here.
Keywords: iav; reporter; fluorescent protein; influenza ... See more keywords