Repositioning approved drugs for the treatment of problematic cancers using a screening approach
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DOI: 10.1371/journal.pone.0171052
Abstract: Advances in treatment strategies together with an earlier diagnosis have considerably increased the average survival of cancer patients over the last four decades. Nevertheless, despite the growing number of new antineoplastic agents introduced each year,… read more here.
Keywords: screening approach; treatment; approved drugs; cancer ... See more keywords
In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets
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DOI: 10.1371/journal.pone.0203340
Abstract: Schistosomiasis is a neglected parasitosis caused by Schistosoma spp. Praziquantel is used for the chemoprophylaxis and treatment of this disease. Although this monotherapy is effective, the risk of resistance and its low efficiency against immature… read more here.
Keywords: mansoni energy; approved drugs; schistosoma mansoni; energy metabolism ... See more keywords