Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders"
DOI: 10.1002/mds.27604
Abstract: Friedreich's ataxia is an autosomal‐recessive cerebellar ataxia caused by mutation of the frataxin gene, resulting in decreased frataxin expression, mitochondrial dysfunction, and oxidative stress. Currently, no treatment is available for Friedreich's ataxia patients. Given that… read more here.
Keywords: drug repositioning; friedreich ataxia; frataxin; ataxia ... See more keywords