Discovery of Compounds That Selectively Repress the Amyloidogenic Processing of the Amyloid Precursor Protein: Design, Synthesis and Pharmacological Evaluation of Diphenylpyrazoles
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DOI: 10.3390/ijms232113111
Abstract: The rationale to define the biological and molecular parameters derived from structure–activity relationships (SAR) is mandatory for the lead selection of small drug compounds. Several series of small molecules have been synthesized based on a… read more here.
Keywords: discovery compounds; selectively repress; amyloidogenic processing; repress amyloidogenic ... See more keywords