Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex.
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DOI: 10.1016/j.devcel.2018.11.018
Abstract: Polycomb repressive complex (PRC) 1 maintains developmental genes in a poised state through monoubiquitination (Ub) of histone H2A. Although Ub-independent functions of PRC1 have also been suggested, it has remained unclear whether Ub-dependent and -independent functions… read more here.
Keywords: fate restriction; repression; prc1; repression prc1 ... See more keywords