CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental cell"
DOI: 10.1016/j.devcel.2020.05.023
Abstract: Evolutionarily conserved signaling pathways are crucial for adjusting growth, reproduction, and cell maintenance in response to altered environmental conditions or energy balance. However, we have an incomplete understanding of the signaling networks and mechanistic changes… read more here.
Keywords: reproductive decline; non autonomously; hedgehog; creb ... See more keywords
Cognitive Changes with Reproductive Aging, Perimenopause, and Menopause.
Sign Up to like & getrecommendations! Published in 2018 at "Obstetrics and gynecology clinics of North America"
DOI: 10.1016/j.ogc.2018.07.011
Abstract: This article reviews the role of endogenous estrogen in neural and cognitive processing, followed by an examination of longitudinal cognitive data captured in various stages of the menopausal transition. The remaining text reviews the contradictory… read more here.
Keywords: changes reproductive; aging perimenopause; cognitive changes; reproductive aging ... See more keywords
Endocrine-Disrupting Chemicals and Female Reproductive Aging
Sign Up to like & getrecommendations! Published in 2025 at "Seminars in Reproductive Medicine"
DOI: 10.1055/s-0044-1801388
Abstract: Abstract Female reproductive aging often affects women's emotional, physical, and physiological well-being. Ovarian aging is characterized by fluctuations in reproductive hormones and determines the age at which menopause occurs. Understanding potentially modifiable factors that influence… read more here.
Keywords: endocrine disrupting; female reproductive; reproductive aging; ovarian reserve ... See more keywords
P-705 Telomere length of white blood cells is a non-invasive marker of reproductive aging in women
Sign Up to like & getrecommendations! Published in 2024 at "Human Reproduction"
DOI: 10.1093/humrep/deae108.1035
Abstract: Can leukocyte telomere length be a marker of ovarian decline? The significant correlation found between leukocyte and cumulus cell telomere lengths supports the use of leukocyte telomere length (TL) as a marker of ovarian aging.… read more here.
Keywords: value; marker; reproductive aging; telomere length ... See more keywords
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction Update"
DOI: 10.1093/humupd/dmab038
Abstract: Abstract BACKGROUND Advanced maternal age is associated with decreased oocyte quantity and quality as well as uterine and placental dysfunctions. These changes lead to infertility, pregnancy complications and birth defects in the offspring. As the… read more here.
Keywords: age; cellular senescence; female reproductive; role ... See more keywords
Effects of menstrual cycle phases and reproductive aging stages on arousal symptoms: observations from the Seattle Midlife Women's Health Study.
Sign Up to like & getrecommendations! Published in 2025 at "Menopause"
DOI: 10.1097/gme.0000000000002570
Abstract: OBJECTIVE Although investigators have devoted significant effort to understanding women's experiences of depressed mood and clinical depression during the menopausal transition and early postmenopause, they have focused less on women's experiences of emotional arousal, including… read more here.
Keywords: cycle phases; menstrual cycle; aging stages; irritability ... See more keywords
Anger, aging, and reproductive aging: observations from the Seattle Midlife Women's Health Study.
Sign Up to like & getrecommendations! Published in 2025 at "Menopause"
DOI: 10.1097/gme.0000000000002587
Abstract: OBJECTIVES Although investigators have devoted significant effort to understanding women's experiences of depressed mood and clinical depression during the menopausal transition and early postmenopause, they have focused less on women's perimenopausal experiences of emotional arousal,… read more here.
Keywords: age; menopausal transition; anger anger; anger ... See more keywords
Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging
Sign Up to like & getrecommendations! Published in 2021 at "Aging Cell"
DOI: 10.1111/acel.13349
Abstract: Cattle are an attractive animal model of fertility in women due to their high degree of similarity relative to follicle selection, embryo cleavage, blastocyst formation, and gestation length. To facilitate future studies of the epigenetic… read more here.
Keywords: methylation; aging epigenetic; model; reproductive aging ... See more keywords
HLA‐DR+ CD45RAˉ Tregs and CD28ˉ Treg‐like cells: Potential immunologic biomarkers for reproductive aging
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13591
Abstract: This study aimed to identify subsets of regulatory T cells (Tregs) associated with ovarian aging and determine whether they can be used as markers of reproductive aging. read more here.
Keywords: cd28 treg; tregs cd28; hla cd45ra; treg like ... See more keywords
Abstract 226: Single variant and gene-based replication analysis of reproductive aging in African American women in the AMBER Consortium
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-226
Abstract: The two main hormonal events of a woman9s life, menarche and menopause, have a paramount impact on the duration of exposure to estrogen. Reproductive aging phenotypes, including age at menarche (AM) and age at natural… read more here.
Keywords: aging african; analysis; gene based; reproductive aging ... See more keywords
Aging and sperm signals alter DNA break formation and repair in the C. elegans germline
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010282
Abstract: Female reproductive aging is associated with decreased oocyte quality and fertility. The nematode Caenorhabditis elegans is a powerful system for understanding the biology of aging and exhibits age-related reproductive defects that are analogous to those… read more here.
Keywords: dna repair; repair elegans; formation; reproductive aging ... See more keywords