Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.01.075
Abstract: SUMMARY Diverse cell types can be reprogrammed into pluripotent stem cells by ectopic expression of Oct4 (Pou5f1), Klf4, Sox3, and Myc. Many of these induced pluripotent stem cells (iPSCs) retain memory, in terms of DNA… read more here.
Keywords: cell; methylation histone; dna methylation; memory ... See more keywords
Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cell Research"
DOI: 10.1016/j.scr.2017.02.011
Abstract: Adult fibroblasts can be reprogrammed into induced pluripotent stem cells (iPSC) for use in various applications. However, there are challenges in iPSC generation including low reprogramming efficiency, yield, cell survival and viability. Since the Hippo… read more here.
Keywords: mst1; proliferation survival; efficiency; cell ... See more keywords
Parabolic relationship between SMAD3 expression level and the reprogramming efficiency of goat induced mammary epithelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1002874
Abstract: Mammary epithelial cells are the only cells of mammary glands with lactation capacity. They are closely related to mammary development and milk yield. Our earlier studies showed that the transformation of goat fibroblasts into induced… read more here.
Keywords: goat; reprogramming efficiency; expression; epithelial cells ... See more keywords