In vivo direct reprogramming of glial linage to mature neurons after cerebral ischemia
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DOI: 10.1038/s41598-019-47482-0
Abstract: The therapeutic effect of in vivo direct reprogramming on ischemic stroke has not been evaluated. In the present study, a retroviral solution (1.5–2.0 × 107 /ul) of mock pMX-GFP (n = 13) or pMX-Ascl1/Sox2/NeuroD1 (ASN) (n = 14) was directly injected… read more here.
Keywords: glial linage; reprogramming glial; cerebral ischemia; direct reprogramming ... See more keywords