High-efficiency RNA-based reprogramming of human primary fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03190-3
Abstract: Induced pluripotent stem cells (iPSCs) hold great promise for regenerative medicine; however, their potential clinical application is hampered by the low efficiency of somatic cell reprogramming. Here, we show that the synergistic activity of synthetic… read more here.
Keywords: medicine; primary fibroblasts; synergistic activity; reprogramming human ... See more keywords
Appropriate Exogenous Expression Stoichiometry of GATA4 as an Important Factor for Cardiac Reprogramming of Human Dermal Fibroblasts.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular reprogramming"
DOI: 10.1089/cell.2022.0014
Abstract: Reprogramming of human dermal fibroblasts (HDFs) into induced cardiomyocyte-like cells (iCMs) represents a promising strategy for human cardiac regeneration. Different cocktails of cardiac transcription factors can convert HDFs into iCMs, although with low efficiency and… read more here.
Keywords: dermal fibroblasts; gata4; stoichiometry; expression ... See more keywords