LAUSR

Reprogramming MHC specificity by CRISPR-Cas9-assisted cassette exchange

Sign Up to like & get
recommendations!
0 Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep45775

Abstract: The development of programmable nucleases has enabled the application of new genome engineering strategies for cellular immunotherapy. While targeted nucleases have mostly been used to knock-out or knock-in genes in immune cells, the scarless exchange… read more here.

Keywords: mhc specificity; reprogramming mhc; crispr cas9; cas9 assisted ... See more keywords