Mbd3 Promotes Reprogramming of Primary Human Fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Stem Cells"
DOI: 10.15283/ijsc18036
Abstract: Mbd3 (Methyl-CpG binding domain protein), a core member of NuRD (nucleosome remodelling and deacetylation) is essential for embryogenesis. However, its role in reprogramming of somatic cells into induced pluripotent stem cells (iPSC) remains controversial. Some… read more here.
Keywords: human fibroblasts; reprogramming primary; primary human; mbd3 promotes ... See more keywords
Protocol Optimization for Direct Reprogramming of Primary Human Fibroblast into Induced Striatal Neurons
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076799
Abstract: The modeling of neuropathology on induced neurons obtained by cell reprogramming technologies can fill a gap between clinical trials and studies on model organisms for the development of treatment strategies for neurodegenerative diseases. Patient-specific models… read more here.
Keywords: reprogramming primary; optimization direct; direct reprogramming; protocol optimization ... See more keywords