Lactate induces metabolic and epigenetic reprogramming of pro‐inflammatory Th17 cells
Sign Up to like & getrecommendations! Published in 2022 at "EMBO reports"
DOI: 10.15252/embr.202254685
Abstract: Increased lactate levels in the tissue microenvironment are a well‐known feature of chronic inflammation. However, the role of lactate in regulating T cell function remains controversial. Here, we demonstrate that extracellular lactate predominantly induces deregulation… read more here.
Keywords: th17 cells; metabolic epigenetic; lactate; reprogramming pro ... See more keywords