Antibodies with Weakly Basic Isoelectric Points Minimize Trade-offs between Formulation and Physiological Colloidal Properties.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00373
Abstract: The widespread interest in antibody therapeutics has led to much focus on identifying antibody candidates with favorable developability properties. In particular, there is broad interest in identifying antibody candidates with highly repulsive self-interactions in standard… read more here.
Keywords: specific interactions; antibody; self interactions; repulsive self ... See more keywords
Emergent synchronization and flocking in purely repulsive self-navigating particles.
Sign Up to like & getrecommendations! Published in 2022 at "Physical review. E"
DOI: 10.1103/physreve.106.044611
Abstract: Inspired by groups of animals and robots, we study the collective dynamics of large numbers of active particles, each one trying to get to its own randomly placed target, while avoiding collisions with each other.… read more here.
Keywords: self navigating; flocking purely; emergent synchronization; repulsive self ... See more keywords