Repurposing auranofin for treatment of Experimental Cerebral Toxoplasmosis.
Sign Up to like & getrecommendations! Published in 2021 at "Acta parasitologica"
DOI: 10.1007/s11686-021-00337-z
Abstract: PURPOSES Evaluate the effect of auranofin on the early and late stages of chronic infection with Toxoplasma gondii avirulent ME49 strain. METHODS Swiss albino mice were orally inoculated with 10 cysts of Toxoplasma gondii, and… read more here.
Keywords: auranofin treatment; treatment; infection; toxoplasmosis ... See more keywords
Repurposing auranofin to combat uropathogenic Escherichia coli biofilms
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.14312
Abstract: The aim of this study was to assess anti‐biofilm and antimicrobial effects of auranofin, an anti‐rheumatic agent, on uropathogenic Escherichia coli (UPEC) biofilm formation. read more here.
Keywords: escherichia coli; uropathogenic escherichia; repurposing auranofin; auranofin combat ... See more keywords
Repurposing auranofin in nonalcoholic fatty liver disease still requires further evidence.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and molecular hepatology"
DOI: 10.3350/cmh.2022.0326
Abstract: and the of nuclear factor kappa B (NF-κB) and inhibitor of NF-κB alpha (IκBα) in LX-2 cells; in HepG2 auranofin erythroid 2-related factor 2 (NRF2) significantly and was required for auranofin to exhibit insulin sensitizing… read more here.
Keywords: nonalcoholic fatty; fatty liver; auranofin nonalcoholic; disease still ... See more keywords