Articles with "repurposing disulfiram" as a keyword



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Repurposing disulfiram for treatment of Staphylococcus aureus infections.

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Published in 2019 at "International journal of antimicrobial agents"

DOI: 10.1016/j.ijantimicag.2019.03.024

Abstract: BACKGROUND Antimicrobial resistance is an urgent threat affecting healthcare systems worldwide. Identification of novel molecules capable of escaping current resistance mechanisms and exhibiting potent activity against highly drug-resistant strains is the unmet need of the… read more here.

Keywords: repurposing disulfiram; disulfiram; staphylococcus aureus; disulfiram treatment ... See more keywords
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Repurposing Disulfiram as an Antifungal Agent: Development of a New Disulfiram Vaginal Mucoadhesive Gel

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Published in 2023 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics15051436

Abstract: Alternative formulations need to be developed to improve the efficacy of treatments administered via the vaginal route. Mucoadhesive gels with disulfiram, a molecule that was originally approved as an antialcoholism drug, offer an attractive alternative… read more here.

Keywords: antifungal agent; development new; disulfiram antifungal; agent development ... See more keywords