Teaching an old dog new tricks: repurposing β-lactams.
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DOI: 10.1016/j.tips.2021.06.003
Abstract: Recently, Martelli and colleagues reported on the structural and functional characterization of new antimycobacterials based on N-thio-β-lactams. Surprisingly, the inhibitory mechanism follows a path unexpected for β-lactams, providing an alternative route to defeat drug-resistant strains… read more here.
Keywords: repurposing lactams; dog new; new tricks; tricks repurposing ... See more keywords