From Repurposing to Redesign: Optimization of Boceprevir to Highly Potent Inhibitors of the SARS-CoV-2 Main Protease
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DOI: 10.3390/molecules27134292
Abstract: The main protease (Mpro) of the betacoronavirus SARS-CoV-2 is an attractive target for the development of treatments for COVID-19. Structure-based design is a successful approach to discovering new inhibitors of the Mpro. Starting from crystal… read more here.
Keywords: boceprevir; protease; repurposing redesign; main protease ... See more keywords