Drug repurposing reveals posaconazole as a CYP11A1 inhibitor enhancing anti-tumor immunity
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DOI: 10.1101/2025.02.21.639414
Abstract: Steroid hormones regulate cell physiology and immune function, with dysregulated steroidogenesis promoting cancer progression by supporting tumour growth and suppressing anti-tumour immunity. Targeting CYP11A1, the first and rate-limiting enzyme in steroid biosynthesis, has shown promise… read more here.
Keywords: drug repurposing; repurposing reveals; immunity; cyp11a1 ... See more keywords