NuA4 acetyltransferase is required for efficient nucleotide excision repair in yeast.
Sign Up to like & getrecommendations! Published in 2019 at "DNA repair"
DOI: 10.1016/j.dnarep.2018.11.006
Abstract: The nucleotide excision repair (NER) pathway is critical for removing damage induced by ultraviolet (UV) light and other helix-distorting lesions from cellular DNA. While efficient NER is critical to avoid cell death and mutagenesis, NER… read more here.
Keywords: nucleotide excision; acetyltransferase; required efficient; excision repair ... See more keywords
MCPH1, mutated in primary microcephaly, is required for efficient chromosome alignment during mitosis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12793-7
Abstract: MCPH1 gene, mutated in primary microcephaly, regulates cell progression into mitosis. While this role has been extensively investigated in the context of DNA damage, its function during unperturbed cell cycles has been given less attention.… read more here.
Keywords: primary microcephaly; mitosis; required efficient; chromosome alignment ... See more keywords
RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes
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DOI: 10.1126/sciadv.abk1789
Abstract: RAD51AP2 is required specifically for efficient meiotic recombination to form crossover between X and Y chromosomes. read more here.
Keywords: rad51ap2 required; required efficient; meiotic recombination; recombination chromosomes ... See more keywords
The L1 stalk is required for efficient export of nascent large ribosomal subunits in yeast.
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DOI: 10.1261/rna.071811.119
Abstract: The ribosomal protein Rpl1 (uL1 in universal nomenclature) is essential in yeast and constitutes part of the L1 stalk which interacts with E site ligands on the ribosome. Structural studies of nascent pre-60S complexes in… read more here.
Keywords: export; ribosomal subunits; required efficient; stalk required ... See more keywords