Articles with "required granule" as a keyword



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Sorting nexin 24 is required for α-granule biogenesis and cargo delivery in megakaryocytes

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Published in 2022 at "Haematologica"

DOI: 10.3324/haematol.2021.279636

Abstract: Germline defects affecting the DNA-binding domain of the transcription factor FLI1 are associated with a bleeding disorder that is characterized by the presence of large, fused α-granules in platelets. We investigated whether the genes showing… read more here.

Keywords: granule biogenesis; sorting nexin; required granule; expression ... See more keywords