Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
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DOI: 10.1038/ncomms14572
Abstract: Expression of PD-L1, the ligand for T-cell inhibitory receptor PD-1, is one key immunosuppressive mechanism by which cancer avoids eradication by the immune system. Therapeutic use of blocking antibodies to PD-L1 or its receptor PD-1… read more here.
Keywords: tumour host; suppression; required mediate; cell required ... See more keywords