Insights into the structural requirements of PKCζ inhibitors as potential anti-arthritis agents based on 3D-QSAR, homology modeling and docking approach
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DOI: 10.1016/j.molstruc.2021.131148
Abstract: Abstract Protein Kinase C ζ (PKCζ) has emerged as a promising novel drug target for the treatment of arthritis. A series of isoquinoline PKCζ inhibitors were analyzed through CoMFA, CoMSIA, homology modeling, and molecular docking… read more here.
Keywords: structural requirements; homology modeling; insights structural; pkc inhibitors ... See more keywords