Differential requirements for P stalk components in activating yeast protein kinase Gcn2 by stalled ribosomes during stress.
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DOI: 10.1073/pnas.2300521120
Abstract: The General Amino Acid Control is a conserved response to amino acid starvation involving activation of protein kinase Gcn2, which phosphorylates eukaryotic initiation factor 2 (eIF2α) with attendant inhibition of global protein synthesis and increased… read more here.
Keywords: gcn2; protein kinase; requirements stalk; kinase gcn2 ... See more keywords