Pentapeptide repeat protein QnrB1 requires ATP hydrolysis to rejuvenate poisoned gyrase complexes
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DOI: 10.1093/nar/gkaa1266
Abstract: Abstract DNA gyrase, a type II topoisomerase found predominantly in bacteria, is the target for a variety of ‘poisons’, namely natural product toxins (e.g. albicidin, microcin B17) and clinically important synthetic molecules (e.g. fluoroquinolones). Resistance… read more here.
Keywords: pentapeptide repeat; atp hydrolysis; gyrase; requires atp ... See more keywords