Nano-based rescue of dysfunctional autophagy in chronic obstructive lung diseases
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DOI: 10.1080/17425247.2016.1223040
Abstract: ABSTRACT Introduction: ΔF508-CFTR (cystic fibrosis transmembrane conductance regulator) is a common CF-mutation that is known to induce oxidative-inflammatory stress through activation of reactive oxygen species (ROS), which induces autophagy-impairment resulting in accumulation of CFTR in… read more here.
Keywords: rescue dysfunctional; dysfunctional autophagy; delivery; drug ... See more keywords