A novel estimand to adjust for rescue treatment in randomized clinical trials.
Sign Up to like & getrecommendations! Published in 2021 at "Statistics in medicine"
DOI: 10.1002/sim.8901
Abstract: The interpretation of randomized clinical trial results is often complicated by intercurrent events. For instance, rescue medication is sometimes given to patients in response to worsening of their disease, either in addition to the randomized… read more here.
Keywords: treatment; randomized clinical; effect; rescue ... See more keywords
Current approaches to handling rescue medication in asthma and eczema randomized controlled trials are inadequate: a systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Epidemiology"
DOI: 10.1016/j.jclinepi.2020.05.027
Abstract: Objectives The objective of this study was to examine how rescue medication is defined, reported, and accounted for in randomized controlled trials (RCTs) in eczema and asthma populations. Study Design and Setting This is a… read more here.
Keywords: use; rescue; eczema; rescue medication ... See more keywords