Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes
Sign Up to like & getrecommendations! Published in 2021 at "genesis"
DOI: 10.1002/dvg.23414
Abstract: Cilia are present on most vertebrate cells and play a central role in development, growth, and homeostasis. Thus, cilia dysfunction can manifest into an array of diseases, collectively termed ciliopathies, affecting millions of lives worldwide.… read more here.
Keywords: candidate ciliopathy; xenopus rescue; rescue model; candidate ... See more keywords
Seizure and redox rescue in a model of glucose transport deficiency
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1012959
Abstract: Disruptions of energy supply to the brain are associated with many neurodegenerative pathologies and are difficult to study due to numerous interlinked metabolic pathways. We explored the effects of diminished energy supply on brain metabolism… read more here.
Keywords: seizure redox; redox rescue; model; rescue model ... See more keywords