The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-deficient hippocampal neurons
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DOI: 10.1186/s13229-019-0293-1
Abstract: BackgroundAlthough neuronal extracellular sensing is emerging as crucial for brain wiring and therefore plasticity, little is known about these processes in neurodevelopmental disorders. Ubiquitin protein ligase E3A (UBE3A) plays a key role in neurodevelopment. Lack… read more here.
Keywords: ligase e3a; contact guidance; guidance; role ... See more keywords