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Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.59371
Abstract: This cohort study uses a large language model to examine changes in research funding from the National Institute of Mental Health (NIMH) for Research Domain Criteria domains and transdiagnostic investigation. read more here.
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Published in 2019 at "Journal of the American Academy of Child and Adolescent Psychiatry"
DOI: 10.1016/j.jaac.2019.07.938
Abstract: OBJECTIVE Research Domain Criteria (RDoC) operationalizes a set of basic social dimensions that can be used to deconstruct sources of variation in social impairments across affected individuals, regardless of their diagnostic status. This step is… read more here.
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Published in 2022 at "Psychological Medicine"
DOI: 10.1017/s0033291721005110
Abstract: Abstract Background The Research Domain Criteria (RDoC) approach proposes a novel psychiatric nosology using transdiagnostic dimensional mechanistic constructs. One candidate RDoC indicator is delay discounting (DD), a behavioral economic measure of impulsivity, based predominantly on… read more here.
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Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-025-55831-z
Abstract: Despite the widespread use of the Research Domain Criteria (RDoC) framework in psychiatry and neuroscience, recent studies suggest that the RDoC is insufficiently specific or excessively broad relative to the underlying brain circuitry it seeks… read more here.
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Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-059232
Abstract: Introduction Obsessive-compulsive and related disorders (OCRDs) and disorders due to addictive behaviours (DABs) are prevalent conditions that share behavioural and neurobiological characteristics. The Research Domain Criteria lists a series of constructs whose dysfunctions may be… read more here.
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Published in 2022 at "Current Directions in Psychological Science"
DOI: 10.1177/09637214211051363
Abstract: The National Institute of Mental Health (NIMH) addressed in its 2008 Strategic Plan an emerging concern that the current diagnostic system was hampering translational research, as accumulating data suggested that the system’s disorder categories constituted… read more here.
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Published in 2021 at "Current medicinal chemistry"
DOI: 10.2174/0929867328666210104104938
Abstract: BACKGROUND Major Depressive Disorder (MDD) and its frequent partial response to antidepressants are a major health concern and therefore an important focus of research. Despite the efforts, MDD pathogenesis and the mechanisms of antidepressant action… read more here.
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Published in 2022 at "Psychiatry Investigation"
DOI: 10.30773/pi.2022.0011
Abstract: Objective Diagnosis of anxiety has relied primarily on self-report. This study aimed to investigate the neural correlates of anxiety with quantitative electroencephalography (qEEG) focusing on the state and trait anxiety defined according to the Research… read more here.
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Published in 2018 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2018.00484
Abstract: Background: Some believe that Psychiatry relies solely on the Diagnostic and Statistical Manual of Mental Disorders (DSM). Some are not aware of the effort initiated by the Research Domain Criteria (RDoC) to propel the field… read more here.
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Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.805163
Abstract: The Research Domain Criteria (RDoC) initiative has been considered a comprehensive alternative classification framework for understanding neuropsychiatric ailments, as opposed to the longstanding, traditional DSM framework. Where the DSM categorizes neuropsychiatric disorders as each being… read more here.