Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.3420
Abstract: Importance Although patients with resected pancreatic adenocarcinoma are at high risk for disease recurrence, few biomarkers are available to inform patient outcomes. Objective To evaluate the alterations of the 4 main driver genes in pancreatic… read more here.
Keywords: patients resected; driver genes; resected pancreatic; pancreatic adenocarcinoma ... See more keywords
Impact of S‐1 adjuvant chemotherapy longer than 6 months on survival in patients with resected pancreatic cancer: a nationwide survey by the Japan Pancreas Society based on real‐world data
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DOI: 10.1002/cncr.34580
Abstract: Based on the Japan Adjuvant Study Group of Pancreatic Cancer 01 study, the standard duration of adjuvant chemotherapy with S‐1 (an oral 5‐fluorouracil prodrug consisting of tegafur, gimeracil, and oteracil) in patients with resected pancreatic… read more here.
Keywords: pancreatic cancer; resected pancreatic; adjuvant chemotherapy; real world ... See more keywords
Phase II clinical trial using novel peptide cocktail vaccine as a postoperative adjuvant treatment for surgically resected pancreatic cancer patients
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DOI: 10.1002/ijc.30510
Abstract: We investigated peptide cocktail vaccine OCV‐C01 containing epitope peptides derived from KIF20A, vascular endothelial growth factor receptor (VEGFR)1 and VEGFR2 combined with gemcitabine in the adjuvant treatment for resected pancreatic cancer patients. A single‐arm multicenter… read more here.
Keywords: resected pancreatic; treatment; pancreatic cancer; peptide cocktail ... See more keywords
Patterns of disease relapse and posttreatment follow‐up of patients with resected pancreatic adenocarcinoma: A single‐center analysis
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DOI: 10.1002/jso.26985
Abstract: To describe the patterns of disease relapse and follow‐up of patients with resected pancreatic adenocarcinoma. Additionally, we looked at patients' characteristics at relapse and survival. read more here.
Keywords: follow patients; resected pancreatic; pancreatic adenocarcinoma; disease relapse ... See more keywords
Clinical Characteristics of Patients With Surgically Resected Pancreatic Cysts: A Retrospective Analysis of 136 Patients
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DOI: 10.1002/jum.16085
Abstract: To retrospectively analyze the characteristics of pancreatic cysts with respect to histopathological diagnosis and various diagnostic imaging tools. read more here.
Keywords: patients surgically; resected pancreatic; pancreatic cysts; surgically resected ... See more keywords
Clinical Impact of Structured Post-Operative Surveillance in Resected Pancreatic Adenocarcinoma: Results from a Retrospective Cohort Study
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DOI: 10.1159/000528722
Abstract: Introduction: To this date, surgery remains the only potentially curative approach in the treatment of pancreatic cancer. To analyse the clinical impact of a structured post-operative follow-up programme, we retrospectively analysed a cohort of resected… read more here.
Keywords: resected pancreatic; adenocarcinoma; pancreatic adenocarcinoma; clinical impact ... See more keywords
Characteristics and outcomes of resected pancreatic cystadenocarcinoma: 1,205 cases from the National Cancer Data Base.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.4129
Abstract: 4129Background: Cystadenocarcinoma (CAC) of the pancreas is a rare pancreatic and therefore there is limited data on the characteristics, treatment and prognosis of this disease. Methods: Patients ... read more here.
Keywords: outcomes resected; resected pancreatic; characteristics outcomes; pancreatic cystadenocarcinoma ... See more keywords
Real-world evidence (RWE) to show improved time to progression among resected pancreatic cancer (RPC) patients receiving adjuvant chemotherapy (adjch).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.4_suppl.242
Abstract: 242Background: Two recent clinical trials (IMPRESS and APACT) suggest the overall survival (OS) of patients with resected pancreatic cancer (RPC) is far longer than previously believed. Improvements in patient selection, intra/post-operative surgical care adjch are… read more here.
Keywords: time progression; resected pancreatic; time; pancreatic cancer ... See more keywords
Association of adjuvant chemotherapy with overall survival in resected pancreatic adenocarcinoma previously treated with neoadjuvant therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.4_suppl.404
Abstract: 404Background: Guidelines for adjuvant chemotherapy in patients with resected pancreatic adenocarcinoma (PDAC) who received neoadjuvant chemotherapy are equivocal. A lymph node ratio (LNR) ≥ 0.15 may predict lack of benefit, but conflicting results are reported.… read more here.
Keywords: chemotherapy; chemotherapy overall; adjuvant chemotherapy; resected pancreatic ... See more keywords
A network meta-analysis of adjuvant systemic therapy in resected pancreatic cancer.
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DOI: 10.1200/jco.2019.37.4_suppl.396
Abstract: 396 Background: Multiple randomized controlled trials (RCTs) have established several systemic therapy regimens as adjuvant therapy treatment options for resected pancreatic cancer, including modified FOLFRINOX (mFFX), gemcitabine and capecitabine (GemCap) and S1, mostly based on… read more here.
Keywords: therapy; resected pancreatic; adjuvant systemic; systemic therapy ... See more keywords
Cost-effectiveness analysis of adjuvant treatment for resected pancreatic cancer in China based on the ESPAC-4 trial
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DOI: 10.2147/cmar.s172704
Abstract: Background The effectiveness of gemcitabine plus capecitabine compared with gemcitabine monotherapy for resected pancreatic cancer has been evaluated in the ESPAC-4 trial. We aimed to assess the cost-effectiveness of these adjuvant regimens on resected pancreatic… read more here.
Keywords: resected pancreatic; pancreatic cancer; cancer; cost effectiveness ... See more keywords