miR-15b-5p resensitizes colon cancer cells to 5-fluorouracil by promoting apoptosis via the NF-κB/XIAP axis
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DOI: 10.1038/s41598-017-04172-z
Abstract: Drug resistance, which is closely correlated with an imbalance in apoptosis, endows colorectal cancer (CRC) with enhanced progression capacity irrespective of the treatment with therapeutics. We report that miR-15b-5p is a tumor suppressor whose level… read more here.
Keywords: apoptosis; resensitizes colon; axis mir; mir 15b ... See more keywords