Preparation of a reserpine certified reference material for calibration and analysis of liquid chromatography
Sign Up to like & getrecommendations! Published in 2019 at "Accreditation and Quality Assurance"
DOI: 10.1007/s00769-019-01412-9
Abstract: A certified reference material (CRM) for reserpine was investigated by raw material purification, qualitative analysis, quantitative analysis, homogeneity testing, stability testing, characterization, and uncertainty evaluation. The candidate reference material was prepared by recrystallization of purchased… read more here.
Keywords: reserpine; reference material; analysis; material ... See more keywords
Changes in the mesocorticolimbic pathway after low dose reserpine-treatment in Wistar and Spontaneously Hypertensive Rats (SHR): Implications for cognitive deficits in a progressive animal model for Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2021 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2021.113349
Abstract: Reserpine (RES) is an irreversible inhibitor of VMAT2 used to study Parkinson's disease (PD) and screening for antiparkinsonian treatments in rodents. Recently, the repeated treatment with a low dose of reserpine was proposed as a… read more here.
Keywords: reserpine; low dose; reserpine treatment; treatment ... See more keywords
Antidepressant-Like Effect of Essential Oils From Citrus reticulata in Reserpine-Induced Depressive Mouse
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DOI: 10.1177/1934578x221093916
Abstract: Citrus reticulata Blanco has been widely used to cure some diseases such as cold, cough and indigestion. This study is aimed at determining the antidepressant-like effect of C. reticulata essential oils (CREOs) in reserpine-induced depression… read more here.
Keywords: citrus reticulata; reserpine; antidepressant like; essential oils ... See more keywords
Preclinical reserpine models recapitulating motor and non-motor features of Parkinson’s disease: Roles of epigenetic upregulation of alpha-synuclein and autophagy impairment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.944376
Abstract: Reserpine is an effective drug for the clinical treatment of hypertension. It also induces Parkinson’s disease (PD)-like symptoms in humans and animals possible through the inhibition of monoamine vesicular transporters, thus decreasing the levels of… read more here.
Keywords: reserpine; non motor; motor; alpha synuclein ... See more keywords
Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects
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DOI: 10.7554/elife.83205
Abstract: Ciliopathies manifest from sensory abnormalities to syndromic disorders with multiorgan pathologies, with retinal degeneration a highly penetrant phenotype. Photoreceptor cell death is a major cause of incurable blindness in retinal ciliopathies. To identify drug candidates… read more here.
Keywords: reserpine; reserpine maintains; rd16 mouse; photoreceptor survival ... See more keywords