Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects
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DOI: 10.7554/elife.83205
Abstract: Ciliopathies manifest from sensory abnormalities to syndromic disorders with multiorgan pathologies, with retinal degeneration a highly penetrant phenotype. Photoreceptor cell death is a major cause of incurable blindness in retinal ciliopathies. To identify drug candidates… read more here.
Keywords: reserpine; reserpine maintains; rd16 mouse; photoreceptor survival ... See more keywords