Qualitative plasma viral load determination as a tool for screening of viral reservoir size in PWH
Sign Up to like & getrecommendations! Published in 2022 at "AIDS"
DOI: 10.1097/qad.0000000000003352
Abstract: Objective(s): Suppression of viral replication in patients on antiretroviral therapy (ART) is determined by plasma viral load (pVL) measurement. Whenever pVL reaches values below the limit of quantification, the qualitative parameter ’target detected’ or ’target… read more here.
Keywords: reservoir; ptd; viral reservoir; pvl ... See more keywords
Serum globulin levels are associated with HIV reservoir size and immune restoration during long‐term ART
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DOI: 10.1111/hiv.13393
Abstract: The objectives of this study were to analyze the relationship between serum globulin levels and immune restoration and HIV reservoir size during long‐term antiretroviral therapy (ART). read more here.
Keywords: hiv; immune restoration; serum globulin; hiv reservoir ... See more keywords
Gut microbiome signatures linked to HIV-1 reservoir size and viremia control
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DOI: 10.1186/s40168-022-01247-6
Abstract: Background The potential role of the gut microbiome as a predictor of immune-mediated HIV-1 control in the absence of antiretroviral therapy (ART) is still unknown. In the BCN02 clinical trial, which combined the MVA.HIVconsv immunogen… read more here.
Keywords: gut microbiome; reservoir size; control; hiv reservoir ... See more keywords
Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size
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DOI: 10.1371/journal.pcbi.1006849
Abstract: Quantitative viral outgrowth assays (QVOA) use limiting dilutions of CD4+ T cells to measure the size of the latent HIV-1 reservoir, a major obstacle to curing HIV-1. Efforts to reduce the reservoir require assays that… read more here.
Keywords: reservoir size; reservoir; outgrowth; size ... See more keywords