Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201646575
Abstract: Immunity to intestinal nematodes requires CD4⁺ Th2‐cell responses, including IL‐4 and IL‐13 production. Chronic infection with intestinal nematodes leads to downregulation of these responses, and few functional T helper (Th) 2 cells are detected in… read more here.
Keywords: highly functional; memory cells; infection; intestinal helminth ... See more keywords
Intestinal CD8+ tissue‐resident memory T cells: From generation to function
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149759
Abstract: Tissue‐resident memory T cells (Trm), and particularly the CD8+ subset, have been shown to play a pivotal role in protection against infections and tumors. Studies in animal models and human tissues have highlighted that, while… read more here.
Keywords: resident memory; tissue resident; memory cells; intestinal cd8 ... See more keywords
Tissue-resident memory T (TRM ) cells: front-line workers of the immune system.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250060
Abstract: Tissue-resident memory T (TRM ) cells play a vital role in local immune protection against infection and cancer. The location of TRM cells within peripheral tissues at sites of pathogen invasion allows for the rapid… read more here.
Keywords: resident memory; tissue resident; memory trm; trm cells ... See more keywords
Pathogenic role of tissue-resident memory T cells in autoimmune diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2018.03.014
Abstract: The tissue-resident memory T (TRM) cells constitute a newly identified subset of memory T cells which are non-circulating and they persist for long-term in epithelial barrier tissues, including skin, lung, gastrointestinal tract and reproductive tract,… read more here.
Keywords: memory cells; autoimmune diseases; tissue resident; trm cells ... See more keywords
Tissue resident memory T cells and viral immunity.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2016.11.011
Abstract: Tissue resident memory T cells (TRM) constitute a recently identified T cell lineage that is responsible for frontline defense against viral infections. In contrast to central and effector memory T cells, which constitutively recirculate between… read more here.
Keywords: cells viral; memory cells; tissue resident; tissue ... See more keywords
Heterogeneity of Tissue Resident Memory T cells.
Sign Up to like & getrecommendations! Published in 2022 at "Immunology letters"
DOI: 10.1016/j.imlet.2022.02.009
Abstract: Non-lymphoid organs, in mice and humans, contain CD8+ tissue-resident memory T (TRM) cells. They play important roles in tissue homeostasis as well as defence against infections and cancer. TRM cells have common characteristics that enables… read more here.
Keywords: trm cells; tissue; resident memory; tissue resident ... See more keywords
Going viral: HBV-specific CD8+ tissue-resident memory T cells propagate anti-tumor immunity.
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.07.014
Abstract: The nature of the epitopes recognized by tumor-infiltrating T cells is not clearly defined. In this issue of Immunity, Cheng et al. demonstrate that tissue-resident memory CD8+ T cells specific for hepatitis B virus-derived antigens exhibit potent anti-tumor… read more here.
Keywords: immunity; tissue resident; anti tumor; resident memory ... See more keywords
Targeting Skin-Resident Memory T Cells via Vaccination to Combat Staphylococcus aureus Infections.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in immunology"
DOI: 10.1016/j.it.2020.11.005
Abstract: Tissue-resident memory T cells are important in adaptive immunity against many infections, rendering these cells attractive potential targets in vaccine development. Genetic and experimental evidence highlights the importance of cellular immunity in protection from Staphylococcus… read more here.
Keywords: skin resident; staphylococcus aureus; memory cells; resident memory ... See more keywords
Tissue-specific differentiation of CD8+ resident memory T cells.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in immunology"
DOI: 10.1016/j.it.2021.08.002
Abstract: CD8+ tissue-resident memory T (TRM) cells play crucial roles in defense against infections and cancer and have been implicated in autoimmune diseases such as psoriasis. In mice and humans, they exist in all nonlymphoid organs… read more here.
Keywords: tissue specific; cd8; trm cells; tissue ... See more keywords
Protective and pathogenic roles of resident memory T cells in human skin disorders.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2019.06.001
Abstract: The human skin is populated by recirculating T cells and skin-sessile resident memory T cells (TRM). Skin TRM are constructed during immune responses against antigens that the host immune system encounters in the skin. TRM… read more here.
Keywords: skin disorders; memory cells; skin; human skin ... See more keywords
IL-1β as mucosal vaccine adjuvant: the specific induction of tissue-resident memory T cells improves the heterosubtypic immunity against influenza A viruses
Sign Up to like & getrecommendations! Published in 2018 at "Mucosal Immunology"
DOI: 10.1038/s41385-018-0017-4
Abstract: A universal influenza vaccine must provide protection against antigenically divergent influenza viruses either through broadly neutralizing antibodies or cross-reactive T cells. Here, intranasal immunizations with recombinant adenoviral vectors (rAd) encoding hemagglutinin (HA) and nucleoprotein (NP)… read more here.
Keywords: influenza viruses; memory cells; tissue resident; mucosal ... See more keywords