Tissue‐resident regulatory T cells accumulate at human barrier lymphoid organs
Sign Up to like & getrecommendations! Published in 2021 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12481
Abstract: Regulatory T cells (Tregs) play a critical role in immune regulation and peripheral tolerance. While different types of Tregs have been identified in both mice and humans, much of our understanding about how these cells… read more here.
Keywords: lymphoid organs; resident tregs; tissue resident; regulatory cells ... See more keywords
Protective role of tissue-resident Tregs in a murine model of beryllium-induced disease
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.156098
Abstract: CD4+ T cells drive the immunopathogenesis of chronic beryllium disease (CBD), and their recruitment to the lung heralds the onset of granulomatous inflammation. We have shown that CD4+ Tregs control granuloma formation in an HLA-DP2… read more here.
Keywords: tissue resident; beryllium; resident tregs; cd4 ... See more keywords