Exploration of Residual Confounding in Analyses of Associations of Metformin Use and Outcomes in Adults With Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.41505
Abstract: This cohort study examines residual confounding in observational studies of off-label metformin in adults with type 2 diabetes. read more here.
Keywords: residual confounding; analyses associations; adults type; type diabetes ... See more keywords
How Effective Are Machine Learning and Doubly Robust Estimators in Incorporating High‐Dimensional Proxies to Reduce Residual Confounding?
Sign Up to like & getrecommendations! Published in 2025 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.70155
Abstract: Residual confounding presents a persistent challenge in observational studies, particularly in high‐dimensional settings. High‐dimensional proxy adjustment methods, such as the high‐dimensional propensity score (hdPS), are widely used to address confounding bias by incorporating proxies for… read more here.
Keywords: dimensional proxies; high dimensional; machine learning; doubly robust ... See more keywords
High‐Dimensional Disease Risk Score for Dealing With Residual Confounding Bias in Estimating Treatment Effects With a Survival Outcome
Sign Up to like & getrecommendations! Published in 2025 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.70172
Abstract: Health administrative databases often contain no information on some important confounders, leading to residual confounding in the effect estimate. We aimed to explore the performance of high‐dimensional disease risk score (hdDRS) to deal with residual… read more here.
Keywords: confounding bias; dimensional disease; disease risk; high dimensional ... See more keywords
Simultaneously Dealing With Immortal Time Bias and Residual Confounding: A Case Study of a High‐Dimensional Propensity Score Approach With a Nested Case–Control Framework in Multiple Sclerosis Research
Sign Up to like & getrecommendations! Published in 2025 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.70174
Abstract: Observational studies of time‐dependent treatments often face immortal time bias and residual confounding, complicating treatment effect estimation. We implemented a high‐dimensional propensity score (hdPS) analysis within a nested case–control (NCC) framework to address both biases… read more here.
Keywords: time; time bias; immortal time; residual confounding ... See more keywords
It's not all about residual confounding: a plea for QBA for epidemiologic researchers and educators.
Sign Up to like & getrecommendations! Published in 2024 at "American journal of epidemiology"
DOI: 10.1093/aje/kwae075
Abstract: We spend a great deal of time on confounding in our teaching, in our methods development and in our assessment of study results. This may give the impression that uncontrolled confounding is the biggest problem… read more here.
Keywords: epidemiology; time; confounding plea; residual confounding ... See more keywords
Reaching the wrong conclusion: residual confounding by indication
Sign Up to like & getrecommendations! Published in 2018 at "Heart"
DOI: 10.1136/heartjnl-2017-312446
Abstract: To the Editor In a recent edition of Heart , Potier et al reported the results of a large, observational analysis of the REACH registry.1 The authors sought to retrospectively compare clinical outcomes in angiotensin… read more here.
Keywords: wrong conclusion; confounding indication; conclusion residual; residual confounding ... See more keywords
Dangers of residual confounding: a cautionary tale featuring cognitive ability, socioeconomic background, and education
Sign Up to like & getrecommendations! Published in 2021 at "BMC Psychology"
DOI: 10.1186/s40359-021-00653-z
Abstract: Background Cognitive ability and socioeconomic background (SEB) have been previously identified as determinants of achieved level of education. According to a “discrimination hypothesis”, higher cognitive ability is required from those with lower SEB in order… read more here.
Keywords: cognitive ability; residual confounding; level education; hypothesis ... See more keywords
Breastfeeding, cognitive ability, and residual confounding: A comment on studies by Pereyra-Elìas et al.
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0297216
Abstract: Recent studies found positive effects of breastfeeding on the child’s cognitive ability and educational outcomes even when adjusting for maternal cognitive ability in addition to a large number of other potential confounders. The authors claimed… read more here.
Keywords: breastfeeding child; ability educational; residual confounding; ability ... See more keywords
Residual Confounding in Health Plan Performance Assessments: Evidence From Randomization in Medicaid
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Internal Medicine"
DOI: 10.7326/m21-0881
Abstract: BACKGROUND Risk adjustment is used widely in payment systems and performance assessments, but the extent to which it distinguishes plan or provider effects from confounding due to patient differences is typically unknown. OBJECTIVE To assess… read more here.
Keywords: plan; performance; population; performance assessments ... See more keywords