Targeting PI3Kγ/AKT Pathway Remodels LC3‐Associated Phagocytosis Induced Immunosuppression After Radiofrequency Ablation
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DOI: 10.1002/advs.202102182
Abstract: Residual tumors after insufficient radiofrequency ablation (IRFA) shows accelerated progression and anti‐PD‐1 resistance. It is also reported that macrophages infiltrating into residual tumors leads to anti‐PD‐1 resistance. Elements of autophagy have been detected to conjugate… read more here.
Keywords: akt pathway; lc3 associated; residual tumors; pi3k akt ... See more keywords
Usefulness of PET-guided surgery with 64Cu-labeled cetuximab for resection of intrapancreatic residual tumors in a xenograft mouse model of resectable pancreatic cancer
Sign Up to like & getrecommendations! Published in 2021 at "Nuclear Medicine Communications"
DOI: 10.1097/mnm.0000000000001442
Abstract: Supplemental Digital Content is available in the text. Background In pancreatic cancer surgery, accurate identification and resection of intrapancreatic residual tumors are quite difficult. We have developed a novel open-typed PET system (called ‘OpenPET’), which… read more here.
Keywords: resection; guided surgery; surgery; residual tumors ... See more keywords
HPV positive, wild type TP53, and p16 overexpression correlate with the absence of residual tumors after chemoradiotherapy in anal squamous cell carcinoma
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DOI: 10.1186/s12876-018-0758-2
Abstract: BackgroundAnal residual tumors are consensually identified within six months of chemoradiotherapy and represent a persistent lesion that may have prognostic value for overall survival. The aim of this study was to evaluate the association of… read more here.
Keywords: residual tumors; absence residual; response; hpv ... See more keywords
Residual tumor model in esophageal squamous cell carcinoma after neoadjuvant immunochemotherapy: Frequently involves the mucosa and/or submucosa
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1008681
Abstract: Objectives The efficacy and safety of neoadjuvant immunochemotherapy (nICT) are widely explored in locally advanced esophageal squamous cell carcinoma (ESCC). Whether the “wait-and-see” strategy is applicable in ESCC after nICT is still lacking a theoretical… read more here.
Keywords: residual tumors; regression; trg; type ... See more keywords
Distribution of residual tumors in esophageal squamous cell carcinoma after neoadjuvant PD-1 blockade combined with chemotherapy
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DOI: 10.3389/fonc.2023.1067897
Abstract: Aims The distribution of residual esophageal squamous cell carcinoma (ESCC) in the esophageal wall and resected lymph nodes was evaluated after neoadjuvant chemoimmunotherapy (nICT). Methods and results Clinical data were collected from 137 ESCC patients… read more here.
Keywords: cell carcinoma; residual tumors; squamous cell; lymph nodes ... See more keywords
Interventional Oncolytic Immunotherapy with LTX-315 for Residual Tumor after Incomplete Radiofrequency Ablation of Liver Cancer
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DOI: 10.3390/cancers14246093
Abstract: Simple Summary Radiofrequency ablation (RFA) is a favorite treatment approach for patients with liver cancer, one of the most common malignancies worldwide. However, incomplete RFA often occurs in irregular and medium-to-larger (>3 cm) hepatic tumors.… read more here.
Keywords: 315 residual; ltx 315; liver; residual tumors ... See more keywords
CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors
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DOI: 10.7554/elife.43653
Abstract: Over half of breast-cancer-related deaths are due to recurrence 5 or more years after initial diagnosis and treatment. This latency suggests that a population of residual tumor cells can survive treatment and persist in a… read more here.
Keywords: cancer recurrence; recurrence; breast cancer; ccl5 promotes ... See more keywords