Specific Residue Interactions Regulate the Binding of Dengue Antigens to Broadly Neutralizing EDE Antibodies
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DOI: 10.1002/open.201800121
Abstract: Abstract Antibodies binding to antigens present on the dengue virus (DENV) represent the main defense mechanism of the host organism against the pathogen. Among the antibodies elicited by DENV and that bind to DII of… read more here.
Keywords: binding dengue; residue interactions; regulate binding; interactions regulate ... See more keywords
Inter-residue interactions in alpha-helical transmembrane proteins
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DOI: 10.1093/bioinformatics/bty978
Abstract: Motivation The number of available membrane protein structures has markedly increased in the last years and, in parallel, the reliability of the methods to detect transmembrane (TM) segments. In the present report, we characterized inter-residue… read more here.
Keywords: transmembrane; membrane proteins; residue interactions; inter residue ... See more keywords
Guiding the folding of G-quadruplexes through loop residue interactions
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DOI: 10.1093/nar/gkac549
Abstract: Abstract A G-rich sequence was designed to allow folding into either a stable parallel or hybrid-type topology. With the parent sequence featuring coexisting species, various related sequences with single and double mutations and with a… read more here.
Keywords: loop; folding quadruplexes; guiding folding; loop residue ... See more keywords