Anchor Residues Govern Binding and Folding of an Intrinsically Disordered Domain.
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DOI: 10.1021/acschembio.2c00619
Abstract: Minimal protein mimics have yielded novel classes of protein-protein interaction inhibitors; however, this success has not been extended to targeting intrinsically disordered proteins, which represent a significant proportion of important therapeutic targets. We sought to… read more here.
Keywords: binding folding; intrinsically disordered; govern binding; anchor residues ... See more keywords